What is the most appropriate action when confirming column degradation during method transfer?
A. Proceed with analysis using adjusted method parameters
B. Document observations and initiate column regeneration
C. Update SOPs to include shorter column lifespan
D. Perform system suitability with reference standard
Answer (2)
The best action when confirming column degradation during method transfer is to document observations and initiate column regeneration, which helps restore the column's performance. This step is essential for maintaining accurate results in chromatography. Option B is the correct answer.
;
When confirming column degradation during method transfer, the most appropriate action is (B) Document observations and initiate column regeneration. ;
