The unique - tertiary structure of the enzyme is what makes it unique - this in combination with the receptors at the active site confer specificity.
B.
The enzyme's surface folds are complementary to the substrate's surface folds.
Enzyme specificity arises from the complementary shape of the enzyme's active site to its substrate, often described by the 'lock and key' model. Additionally, as substrates bind, enzymes may undergo conformational changes to enhance the fit and stabilize the reaction. Each enzyme typically catalyzes a specific reaction type, although some can act on structurally similar substrates.
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