If a mother carries a recessive allele for a genetic disorder, such as cystic fibrosis, under what circumstances will her children inherit the disorder?

A. The children's father must also carry the recessive allele.
B. The mother's father must also carry the recessive allele.
C. The paternal grandfather must also carry the recessive allele.
D. The children must be female like the mother to inherit the disorder.

The children's father must also carry the recessive allele. Recessive alleles only determine characteristics when a child inherits a copy from each parent.

Answered by jwainwright54jack | 2024-06-10

Answer:
The correct answer would be "**The children's father must also carry the recessive allele". **
Cystic fibrosis is an autosomal recessive disorder. Thus, a person must homozygous recessive in order to produce a phenotype.
Let C and c be the allele of the gene responsible for the disease. C is the dominant allele which codes for normal physiology and c be the recessive allele which codes for the disease when present in homozygous condition.
The mother is the carrier of the diseases that means she is heterozygous (Cc) for the disease.
In order that her children would get the disease, the father must carry c allele. He can be Cc or cc.

Answered by JoiePatel | 2024-06-24

To inherit cystic fibrosis, the child must receive two copies of the recessive allele, which means both parents need to contribute the recessive allele. Therefore, the father must also carry the recessive allele for the children to inherit the disorder. The correct answer is option A: 'The children's father must also carry the recessive allele.'
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Answered by JoiePatel | 2024-10-01